PUBLICATIONS
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Peer-Reviewed Publications
Manuscripts (Solomon Lab personnel; ‡ equal contribution)
2024
  1. AA Stepnov, E Lopez Tavera, RR Klauer, CL Lincoln, RR Chowreddy, GT Beckham, VGH Eijsing, KV Solomon, MA Blenner*, G Vaaje-Kolstad*, Revisiting the activity of two poly(vinyl chloride)- and polyethylene-degrading enzymes, Nature Communications, 15 (1): 8501 (2024).
  2. ER. Aurand*, TS Moon, NR Buan, KV Solomon, M Köpke, EBRC Technical Roadmapping Working Group, Addressing the Climate Crisis Through Engineering Biology, npj Climate Action, 3, 9 (2024).
  3. RR Klauer, DA Hansen‡, D Wu‡, LM Oliveira Monteiro‡, KV Solomon*, MA Blenner*, Biological Upcycling of Plastic Waste, Ann Rev Chem Eng, 15: 14.1-14.28 (2024). 
  4. B Graver, N Chakravarty, KV Solomon*, Prokaryotic argonautes for in vivo biotechnology and molecular diagnostics, Trends in Biotechnology,  42 (1): 61-73 (2024). 
2023
  1. AJ Vaidya‡ , M Rammohan‡ , YH Lee‡, KZ Lee‡, CY Chou, Z Hartley, CA Scott, RG Susler, L Wang, LS Loesch-Fries, MT Harris, KV Solomon*, Engineering Alkaline-Stable Barley Stripe Mosaic Virus-Like Particles for Efficient Surface Modification, Biochemical Engineering Journal, 199: 109062 (2023). 
  2. TS Moon, KV Solomon, I Borodina, C Vickers, Impacting future generations of synthetic biologists by ensuring diversity, equity, and inclusion, Trends in Biotechnology, 41 (9): 1099-1105 (2023). 
  3. CH Hooker, R Hanafy, ET Hillman, J Muñoz, KV Solomon, A genetic engineering toolbox for the lignocellulolytic anaerobic gut fungus Neocallimastix frontalis, ACS Synthetic Biology, 12 (4): 1034-1045  (2023). 
2022
  1. ET Hillman, LE Caceres Martinez, G Kilaz, KV Solomon, Top-down engineering of oil field microbiomes to limit souring and control oil composition during extraction operations.  AIChE Journal, 68 (12): e17927 (2022).
  2. MS Elshahed*, RA Hanafy, Y Cheng, SS Dagar, JE Edwards, V Flad, KO Fliegerová, GW Griffith, S Kittelmann, M Lebuhn, MA O’Malley, SM Podmirseg, KV Solomon, J Vinzelj, D Young, and NH. Youssef. Characterization and rank assignment criteria for the anaerobic fungi (Neocallimastigomycota), International Journal of Systematic and Evolutionary Microbiology, 72 (7): 005449 (2022) 
  3. ​​​AJ Vaidya, KV Solomon*, Surface Functionalization of Rod Shaped Viral-Like Particles for Biomedical Applications. ​ACS Appl Bio Mater 5 (5): 1980-1989 (2022).
  4. KZ Lee‡, MA Mechikoff‡,  M Parasa, P Pandolfi, K Fitzgerald, E Hillman, KV Solomon*, Repurposing the homing endonuclease I-SceI for positive selection and development of gene-editing technologies, ACS Syn Biol, 11 (1): 53-60 (2022).
2021
  1. ​ET Hillman, E Frazier, E Shank, A Ortiz-Velez, J Englaender, KV Solomon*, Anaerobic fungal mevalonate pathway genomic biases lead to heterologous toxicity underpredicted by codon adaptation indices, Microorganisms, 9 (9):1986 (2021).
  2. KZ Lee, MA Mechikoff, A Kikla, A Liu, P Pandolfi, K Fitzgerald, FS Gimble, KV Solomon*, NgAgo possesses guided DNA nicking activity, Nucleic Acids Research, 49 (17): 9926-9937, 2021.  
  3. CL Swift, KB Louie, BP. Bowen, CA Hooker, KV Solomon, V Singan, C Daum, CP Pennacchio, K Barry. V Shutthanandan, JE Evans, IV Grigoriev, TR Northen, MA O’Malley*, Co-cultivation of anaerobic fungi with rumen bacteria establishes an antagonistic relationship, mBio, 12(4): e01442-21 (2021)
  4. ET Hillman, M Li, CA Hooker, J Englaender, IR Wheeldon, KV Solomon*, Hydrolysis of lignocellulose by anaerobic fungi produces free sugars and organic acids for two-stage fine chemical production with Kluyveromyces marxianus, Biotechnology Progress,37(5): e3172 (2021).
  5. J Beal*, GS. Baldwin*, ….. iGEM Interlab Study Contributors (including E Foster, J Rickus, KV Solomon), Comparative analysis of three studies measuring fluorescence from engineered bacterial genetic constructs, PLoS ONE, 16(6): : e0252263 (2021).
  6. CL Swift, KB Louie, BP Bowen, HM Brewer, SO Purvine, A Salamov, SJ Mondo, KV Solomon, AT Wright, TR Northen, IV Grigoriev, NP Keller, MA O’Malley*, Anaerobic gut fungi are an untapped reservoir of natural products, PNAS, 118 (18): e2019855118 (2021).
  7. KZ Lee, V Basnayake Pussepitiya, YH Lee, S Loesch-Fries, M Harris, S Hemmati, KV Solomon*, Engineering Tobacco Mosaic Virus and its Virus-Like-Particles for Synthesis of Biotemplated Nanomaterials, Biotechnology Journal, 16 (4): 200311 (2021)​.
  8. C Sweet, A Aayush, LR Readnour, KV Solomon, DH Thompson*, Development of a Fast Organic Extraction-Precipitation Method for Improved Purification of Elastin-like Polypeptides that is Independent of Sequence and Molecular Weight. Biomacromolecules, 22 (5): 1990-1998 (2021).
2020
  1. YH Lee‡, KZ Lee‡, RG. Susler, CA. Scott,  L Wang, LS Loesch-Fries, MT Harris, KV Solomon*, Bacterial production of Barley Stripe Mosaic Virus Biotemplates for Palladium Nanoparticle Growth, ACS Applied Nano Materials​, 3 (12): 12080 - 12086 (2020).
2019
  1. C Hooker, KZ Lee, KV Solomon*, Leveraging the biotechnology potential of anaerobic fungi, Current Opinion in Biotechnology, 59:103-110 (2019). (invited).
  2. RM RedCorn, ET Hillman, KV Solomon, AS Engelberth*, Xanthobacter-dominated biofilm as a novel source for high-value rhamnose, Applied Microbiology & Biotechnology, 103 (11):4525-4538 (2019).
​2018
  1. C Hooker, E Hillman, J Overton, A Ortiz-Velez, M Schacht, A Hunnicutt, N Mosier, KV Solomon*, Hydrolysis of untreated lignocellulosic feedstock is independent of S-lignin composition in newly classified anaerobic fungal isolate, Piromyces sp. UH-31, Biotechnology for Biofuels​, 11:293 (2018).
  2. KV Solomon, SP Gilmore, JK Henske, D Thompson, MA O’Malley. Catabolic repression in early-diverging anaerobic fungi is partially mediated by natural antisense transcripts , Fungal Genetics & Biology, 121: 1-9 (2018). 
  3. JK Henske, SP Gilmore, CH Haitjema, KV Solomon, MA O’Malley.  Biomass‐degrading Enzymes are Catabolite Repressed in Anaerobic Gut Fungi​, AIChE J,  64:4263-4270 (2018). (Invited Article, Founders Issue Honoring Jay Bailey)
  4. J Beal*, T Haddock-Angelli*, G Baldwin*, M Gersharter, A Dwijayanti, M Storch, M Lizarazo, R Rettberg, iGEM Interlab Study Contributors (including E Foster, J Rickus, KV Solomon), Quantification of Bacterial Fluorescence using Independent Calibrants, PLoS ONE, 13(6): e0199432 (2018).
  5. JK Henske, SE Wilken, KV Solomon, CE Smallwood, V Shutthanandan, JE Evans, MK Theodorou, MA O’Malley. Metabolic characterization of anaerobic fungi provides a path forward for consolidated bioprocessing of crude lignocellulose, Biotechnology & Bioengineering, 115: 874-884 (2018).
2017
  1. S Seppälä, SE Wilken, D Knop, KV Solomon, MA O’Malley. The importance of sourcing enzymes from non-conventional fungi for metabolic engineering & biomass breakdown, Metabolic Engineering,44: 45-59 (2017). 
  2. SP Gilmore, JK Henske, JA Sexton, KV Solomon , S Seppälä, JI Yoo, LM Huyett, A Pressman, JZ Cogan, V Kivenson, X Peng, YP Tan, DL Valentine, MA O’Malley*. Genomic analysis of methanogenic archaea reveals a shift towards energy conservation, BMC Genomics, 18:639 (2017).
  3. ET Hillman, LR Readnour, KV Solomon. Exploiting the natural product potential of fungi with integrated -omics and synthetic biology approaches, Current Opinion in Systems Biology,​ 5: 50-56 (2017).
  4. CH Haitjema, SP Gilmore, JK Henske, KV Solomon, R de Groot, A Kuo, S Mondo, AA Salamov, K LaButti, Z Zhao, J Chinquy, K Barry, HM Brewer, SO Purvine, AT Wright, B Boxma, T van Alen, JHP Hackstein, SE Baker, K Barry, IV Grigoriev, MA O’Malley, A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics, Nature Microbiology, 2:17087, (2017)
  5. S Mohan, C Roleck, P Rudin, B Clark, E Foster, A Kikla, S Magill, M Aronson, R Budde, H Kubo, A Liu, H Lysandrou, C Martin, A Petrucciani, J Welch, S Ha, J Rickus, K Solomon. iGEM REPORT: Engineering E. coli for phosphate bioremediation, PLOS Collections, 17-05 (2017).
2016
  1. S Seppälä, KV Solomon, SP Gilmore, JK Henske, MA O’Malley, Mapping the membrane proteome of anaerobic gut fungi identifies a wealth of carbohydrate binding proteins and transporters, Microbial Cell Factories, 15: 212, (2016).
  2. GJ Li et. al (+140 additional authors, including KV Solomon, JK Henske, CH Haitjema, SP Gilmore, MK Theodorou, MA O'Malley), Fungal diversity notes 253-366: taxonomic and phylogenetic contributions to fungal taxa, Fungal Diversity, 78 (1): 1-237, (2016).
  3. KV Solomon, E Ovadia, F Yu, W Mizunashi, MA . Mitochondrial targeting increases specific activity of a heterologous valine assimilation pathway in Saccharomyces cerevisiae, Metabolic Engineering Communications, 3: 68-75 (2016).
  4. KV Solomon, CH Haitjema, JK Henske, SP Gilmore, D Borges-Rivera, A Lipzen, HM Brewer, SO Purvine, AT Wright, MK Theodorou, IV Grigoriev, A Regev, DA Thompson, MA O’Malley. Early-branching gut fungi possess a large, comprehensive array of biomass degrading enzymes, Science​, 351: 1192-1195  (2016).
  5. KV Solomon, JK Henske, MK Theodorou, MA O’Malley. Robust and effective cryopreservation and DNA extraction from gut fungi, Anaerobe, 38: 39 – 46 (2016).
​2014
  1. CH Haitjema, KV Solomon, JK Henske, MK Theodorou, MA O’Malley. Anaerobic gut fungi: Advances in isolation, culture, and cellulolytic enzyme discovery for biofuel production . Biotechnology and Bioengineering, 111: 1471–1482 (2014).
  2. KV Solomon, CH Haitjema, DA Thompson, MA O’Malley. Extracting data from the muck: deriving biological insight from complex microbial communities and non-model organisms with next generation sequencing.  Current Opinion in Biotechnology, 28:103-110 (2014).
​2013 and earlier
  1. KV Solomon, TS Moon, B Ma, TM Sanders, KLJ Prather.,Tuning primary metabolism for heterologous productivity.  ACS Synthetic Biology, 2(3):126-135 (2013). 
  2. KV Solomon, TM Sanders, KLJ Prather, A dynamic metabolite valve for the control of central carbon metabolism.  Metabolic Engineering, 14(6): 661-671 (2012).
  3. KV Solomon and KLJ Prather. The zero-sum game of pathway optimization: Emerging paradigms for tuning gene expression .  Biotechnology Journal, 6(9), 1064-1070 (2011).
  4. CH Martin, DR Nielsen, KV Solomon & KLJ Prather. Synthetic Metabolism: Engineering biology at the protein and pathway scales. Chemistry & Biology, 16, 277-286 (2009).
  5. E Leonard, D Nielsen, K Solomon, & KJ Prather. Engineering microbes with synthetic biology frameworks.  Trends in Biotechnology, 26, 674-681 (2008).​
Book Chapters
  1. MA Mechikoff‡, KZ Lee‡, KV Solomon*. Positive Selection Screens for Programmable Endonuclease Activity using I-SceI, in: Synthetic Biology - Methods and Protocols, Second Edition (Methods in Molecular Biology series). ed by Jeffrey Braman, in press. (Springer)
  2. V Dollhofer*, D Young, SM Podmirseg, M Reilly, Y Li, C Hooker, K Solomon, M Elshahed, N Youssef, K Fliegerová, Y Chen, GW Griffith, MK Theodorou, M O’Malley. The biotechnological potential of anaerobic gut fungi, in: The Mycota Vol. II: Genetics and Biotechnology, 3rd ed., ed. by J. Philipp Benz and Kerstin Schipper , 2020 (Springer)
  3. M Ladisch, E Ximenes, N Mosier, A Engelberth, K Solomon, Bioprocess Engineering, in: Industrial Microbiology, Wiley, in: Industrial Microbiology, 1st ed., ed. By DB Wilson, H Sahm, KP Stahmann, M Koffas, 2019 (Wiley)
Congressional Testimony
Patents & Technology Disclosures
Picture
Patents Granted
  • Kevin Solomon, Kok Zhi Lee, Michael Harris, Yu-Hsuan Lee, Loretta Sue Loesch-Fries. Nanoparticles And Biotemplates With Tunable Length And Methods Of Manufacturing The Same, US Patent 11,820,988, issued 21 Nov 2023.
  • Kevin Solomon, Kok Zhi Lee, Ethan Hillman, Yu Hong Wang. Tunable, synthetic transcriptional regulators responsive to environmental triggers, US Patent 11,352,632, issued 7 June 2022. 
  • Michelle A. O’Malley, Kevin V. Solomon, and Charles H. Haitjema. Proteins from Anaerobic Fungi and Uses Thereof, US Patent 10,717,768, issued Jul 21, 2020.
  • Michelle A. O'Malley, Kevin V. Solomon. Bioproduction of Methyl Methacrylate, U.S. Patent 10,676,766, issued Jun 9, 2020.
  • Kevin Solomon, Tae Seok Moon, Kristala L Prather. Glucose Valves and other Metabolite Valves, US Patent 8,835,138, issued 16 Sep 2014. 

​Patents Pending
  • Mark Blenner, Kevin Solomon, Ross Klauer. Biological and biomolecular recovery of plastic waste, Disclosure UD 23-11 filed November 7, 2022, US Provisional Patent Application 63/564,161 filed March 12, 2024.
  • Kevin Solomon, Kok Zhi Lee, Akash Vaidya, Mruthula Rammohan, Continuation patent application to: Nanoparticles And Biotemplates With Tunable Length And Methods Of Manufacturing The Same, US Provisional Patent Application 18/516,243, filed 21 Nov 2023.
  • Mark Blenner, Kevin Solomon, Lummy Monteiro, Jyoti Singh, Ross Klauer. UD22-32: Optimizing Plastic Degradation by Yellow Mealworms and Their Gut Microbiomes, US Provisional Patent Application 63/336,657, filed April 29, 2022
  • Kevin Solomon, Kok Zhi Lee. NgAgo as a DNA-guided gene editing tool in prokaryotes and eukaryotes, US Provisional Patent Application 62/643, 814, filed Mar 2018, patent pending.